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Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1
Spinocerebellar ataxias are neurodegenerative diseases, the hallmark symptom of which is the development of ataxia due to cerebellar dysfunction. Purkinje cells, the principal neurons of the cerebellar cortex, are the main cells affected in these disorders, but the sequence of pathological events le...
Autores principales: | Osório, Catarina, White, Joshua J, Lu, Heiling, Beekhof, Gerrit C, Fiocchi, Francesca Romana, Andriessen, Charlotte A, Dijkhuizen, Stephanie, Post, Laura, Schonewille, Martijn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232256/ https://www.ncbi.nlm.nih.gov/pubmed/36352508 http://dx.doi.org/10.1093/brain/awac422 |
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