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TRPM2 Mediates Hepatic Ischemia–Reperfusion Injury via Ca(2+)-Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression

Hepatic ischemia–reperfusion (IR) injury is a serious clinical problem that complicates liver resection and transplantation. Despite recent advances in understanding of the pathophysiology of hepatic IR injury, effective interventions and therapeutics are still lacking. Here, we examined the role of...

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Detalles Bibliográficos
Autores principales: Zhong, Cheng, Yang, Jing, Zhang, Yiyin, Fan, Xiaoxiao, Fan, Yang, Hua, Ning, Li, Duguang, Jin, Shengxi, Li, Yirun, Chen, Peng, Chen, Yongle, Cai, Xiaobo, Zhang, Yi, Jiang, Linhua, Yang, Wei, Yu, Peilin, Lin, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232356/
https://www.ncbi.nlm.nih.gov/pubmed/37275121
http://dx.doi.org/10.34133/research.0159