Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies

While regulatory T (T(reg)) cells are traditionally viewed as professional suppressors of antigen presenting cells and effector T cells in both autoimmunity and cancer, recent findings of distinct T(reg) cell functions in tissue maintenance suggest that their regulatory purview extends to a wider ra...

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Detalles Bibliográficos
Autores principales: Glasner, Ariella, Rose, Samuel A., Sharma, Roshan, Gudjonson, Herman, Chu, Tinyi, Green, Jesse A., Rampersaud, Sham, Valdez, Izabella K., Andretta, Emma S., Dhillon, Bahawar S., Schizas, Michail, Dikiy, Stanislav, Mendoza, Alejandra, Hu, Wei, Wang, Zhong-Min, Chaudhary, Ojasvi, Xu, Tianhao, Mazutis, Linas, Rizzuto, Gabrielle, Quintanal-Villalonga, Alvaro, Manoj, Parvathy, de Stanchina, Elisa, Rudin, Charles M., Pe’er, Dana, Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232368/
https://www.ncbi.nlm.nih.gov/pubmed/37127830
http://dx.doi.org/10.1038/s41590-023-01504-2

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