Cargando…

Individual-specific functional connectivity improves prediction of Alzheimer’s disease’s symptoms in elderly people regardless of APOE ε4 genotype

To date, reliable biomarkers remain unclear that could link functional connectivity to patients’ symptoms for detecting and predicting the process from normal aging to Alzheimer’s disease (AD) in elderly people with specific genotypes. To address this, individual-specific functional connectivity is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hua, Lin, Gao, Fei, Xia, Xiaoluan, Guo, Qiwei, Zhao, Yonghua, Huang, Shaohui, Yuan, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232409/ https://www.ncbi.nlm.nih.gov/pubmed/37258640 http://dx.doi.org/10.1038/s42003-023-04952-6

Ejemplares similares

Impact of APOE ε4 genotype on initial cognitive symptoms differs for Alzheimer’s and Lewy body neuropathology
por: Pillai, Jagan A., et al.
Publicado: (2021)

Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease
por: Mishra, Aarti, et al.
Publicado: (2018)

Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
por: Arnold, Matthias, et al.
Publicado: (2020)

Genotypic effects of APOE-ε4 on resting-state connectivity in cognitively intact individuals support functional brain compensation
por: Cacciaglia, Raffaele, et al.
Publicado: (2022)

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
por: Baek, Min Seok, et al.
Publicado: (2020)

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
por: Konijnenberg, Elles, et al.
Publicado: (2020)

APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia
por: Blackman, Jonathan, et al.
Publicado: (2022)

Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status
por: Mun, Ye Sol, et al.
Publicado: (2022)

Association between APOE ε4 Genotype and Memory Impairment in Elderly with Normal Global Cognitive Assessment
por: Turana, Yuda, et al.
Publicado: (2015)

Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease
por: Kerestes, Rebecca, et al.
Publicado: (2015)

Impact of sex and APOE-ε4 genotype on patterns of regional brain atrophy in Alzheimer's disease and healthy aging
por: Sauty, Benoît, et al.
Publicado: (2023)

The APOE(ε3/ε4) Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
por: Foley, Kate E., et al.
Publicado: (2022)

APOE genotype and Alzheimer’s immunotherapy
por: Pankiewicz, Joanna E., et al.
Publicado: (2017)

Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis
por: Momkute, Liucija, et al.
Publicado: (2022)

Differences in resting-state brain networks and gray matter between APOE ε2 and APOE ε4 carriers in non-dementia elderly
por: Wang, Zhiyuan, et al.
Publicado: (2023)

APOE ε4, an Alzheimer’s disease susceptibility allele, and smoking cessation
por: Ashare, Rebecca L., et al.
Publicado: (2012)

Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease
por: Bonham, Luke W., et al.
Publicado: (2016)

APOEε4 and risk of Alzheimer’s disease – time to move forward
por: Lefterov, Iliya, et al.
Publicado: (2023)

Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
por: Kulminski, Alexander M., et al.
Publicado: (2022)

Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia
por: Salvadó, Gemma, et al.
Publicado: (2021)

Proteomic Network Analysis of Alzheimer’s Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment
por: Dammer, Eric B., et al.
Publicado: (2023)

Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease
por: Caesar, Ina, et al.
Publicado: (2012)

Bioenergetic and inflammatory systemic phenotypes in Alzheimer’s disease APOE ε4‐carriers
por: Wilkins, Heather M., et al.
Publicado: (2021)

Reduced Physiological Complexity in Robust Elderly Adults with the APOE ε4 Allele
por: Cheng, Daniel, et al.
Publicado: (2009)

Dissecting the Gene Dose-Effects of the APOE ε4 and ε2 Alleles on Hippocampal Volumes in Aging and Alzheimer’s Disease
por: Hostage, Christopher A., et al.
Publicado: (2013)

Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice
por: Pankiewicz, Joanna E, et al.
Publicado: (2014)

Striatonigrostriatal connectivity‐based cross‐species parcellation of human and macaque substantia nigra
por: Xia, Xiaoluan, et al.
Publicado: (2023)

Apolipoprotein E (ApoE) ε4 Genotype (ApoE rs429358—ApoE rs7412 Polymorphisms) Is Not Associated with Long COVID Symptoms in Previously Hospitalized COVID-19 Survivors
por: Fernández-de-las-Peñas, César, et al.
Publicado: (2023)

Effects of sex and APOE ε4 genotype on brain mitochondrial high-energy phosphates in midlife individuals at risk for Alzheimer’s disease: A (31)Phosphorus MR spectroscopy study
por: Jett, Steven, et al.
Publicado: (2023)

Association between an Alzheimer’s Disease-Related Index and APOE ε4 Gene Dose
por: Schraml, Frank, et al.
Publicado: (2013)

Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality
por: Mez, Jesse, et al.
Publicado: (2017)

Rate of brain aging and APOE ε4 are synergistic risk factors for Alzheimer’s disease
por: Glorioso, Christin A, et al.
Publicado: (2019)

THE APOE-ε4 ALLELE AND AGE SYNERGISTICALLY DRIVE DISEASE PROGRESSION IN ALZHEIMER’S DISEASE
por: Kleineidam, Luca, et al.
Publicado: (2019)

APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia
por: Mirza, Saira Saeed, et al.
Publicado: (2019)

Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity
por: Vardarajan, Badri, et al.
Publicado: (2020)

The APOE ε4 exerts differential effects on familial and other subtypes of Alzheimer's disease
por: Jia, Longfei, et al.
Publicado: (2020)

APOE-ε4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease
por: Hou, Min, et al.
Publicado: (2021)

Peripheral apoE isoform levels in cognitively normal APOE ε3/ε4 individuals are associated with regional gray matter volume and cerebral glucose metabolism
por: Nielsen, Henrietta M., et al.
Publicado: (2017)

ε2 allele and ε2-involved genotypes (ε2/ε2, ε2/ε3, and ε2/ε4) may confer the association of APOE genetic polymorphism with risks of nephropathy in type 2 diabetes: a meta-analysis
por: Shi, Jikang, et al.
Publicado: (2020)

Cognitive decline is related to high blood glucose levels in older Chinese adults with the ApoE ε3/ε3 genotype
por: Qiu, Qi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_27l73p0h16rs9fqfe6pmb2hf4v