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Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes

Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable. Here we show a homogeneous copper-catalyzed hetero Diels−Alder (HDA) reaction of allenynes...

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Detalles Bibliográficos
Autores principales: Wei, Kua-Fei, Liu, Qing, Ma, Guang, Jiang, Xiao-Lei, Zhu, Xiu-Hong, Ru, Guang-Xin, Shen, Wen-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232412/
https://www.ncbi.nlm.nih.gov/pubmed/37258704
http://dx.doi.org/10.1038/s42004-023-00910-9