Identification of photocrosslinking peptide ligands by mRNA display

Photoaffinity labelling is a promising method for studying protein-ligand interactions. However, obtaining a specific, efficient crosslinker can require significant optimisation. We report a modified mRNA display strategy, photocrosslinking-RaPID (XL-RaPID), and exploit its ability to accelerate the...

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Detalles Bibliográficos
Autores principales: Wu, Yuteng, Bertran, M. Teresa, Joshi, Dhira, Maslen, Sarah L., Hurd, Catherine, Walport, Louise J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232439/
https://www.ncbi.nlm.nih.gov/pubmed/37258712
http://dx.doi.org/10.1038/s42004-023-00898-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232439/
https://www.ncbi.nlm.nih.gov/pubmed/37258712
http://dx.doi.org/10.1038/s42004-023-00898-2

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