Alveolar epithelial cells are competent producers of interstitial extracellular matrix with disease relevant plasticity in a human in vitro 3D model

Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. We examined the capacity of AEC to produce extracellular matrix (ECM) and thereby directly contribute towards remodelling in chronic lung diseases. Cryopreserved type 2 AEC (AEC2) from healthy lungs and chronic obstruc...

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Detalles Bibliográficos
Autores principales: Rosmark, Oskar, Kadefors, Måns, Dellgren, Göran, Karlsson, Christofer, Ericsson, Anders, Lindstedt, Sandra, Malmström, Johan, Hallgren, Oskar, Larsson-Callerfelt, Anna-Karin, Westergren-Thorsson, Gunilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232446/
https://www.ncbi.nlm.nih.gov/pubmed/37258541
http://dx.doi.org/10.1038/s41598-023-35011-z

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