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Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence
The ventromedial prefrontal-cortex (vmPFC) is known to contain expected value signals that inform our choices. But expected values even for the same stimulus can differ by task. In this study, we asked how the brain flexibly switches between such value representations in a task-dependent manner. Thi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232498/ https://www.ncbi.nlm.nih.gov/pubmed/37258534 http://dx.doi.org/10.1038/s41467-023-38709-w |
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author | Moneta, Nir Garvert, Mona M. Heekeren, Hauke R. Schuck, Nicolas W. |
author_facet | Moneta, Nir Garvert, Mona M. Heekeren, Hauke R. Schuck, Nicolas W. |
author_sort | Moneta, Nir |
collection | PubMed |
description | The ventromedial prefrontal-cortex (vmPFC) is known to contain expected value signals that inform our choices. But expected values even for the same stimulus can differ by task. In this study, we asked how the brain flexibly switches between such value representations in a task-dependent manner. Thirty-five participants alternated between tasks in which either stimulus color or motion predicted rewards. We show that multivariate vmPFC signals contain a rich representation that includes the current task state or context (motion/color), the associated expected value, and crucially, the irrelevant value of the alternative context. We also find that irrelevant value representations in vmPFC compete with relevant value signals, interact with task-state representations and relate to behavioral signs of value competition. Our results shed light on vmPFC’s role in decision making, bridging between its role in mapping observations onto the task states of a mental map, and computing expected values for multiple states. |
format | Online Article Text |
id | pubmed-10232498 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-102324982023-06-02 Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence Moneta, Nir Garvert, Mona M. Heekeren, Hauke R. Schuck, Nicolas W. Nat Commun Article The ventromedial prefrontal-cortex (vmPFC) is known to contain expected value signals that inform our choices. But expected values even for the same stimulus can differ by task. In this study, we asked how the brain flexibly switches between such value representations in a task-dependent manner. Thirty-five participants alternated between tasks in which either stimulus color or motion predicted rewards. We show that multivariate vmPFC signals contain a rich representation that includes the current task state or context (motion/color), the associated expected value, and crucially, the irrelevant value of the alternative context. We also find that irrelevant value representations in vmPFC compete with relevant value signals, interact with task-state representations and relate to behavioral signs of value competition. Our results shed light on vmPFC’s role in decision making, bridging between its role in mapping observations onto the task states of a mental map, and computing expected values for multiple states. Nature Publishing Group UK 2023-05-31 /pmc/articles/PMC10232498/ /pubmed/37258534 http://dx.doi.org/10.1038/s41467-023-38709-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Moneta, Nir Garvert, Mona M. Heekeren, Hauke R. Schuck, Nicolas W. Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title | Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title_full | Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title_fullStr | Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title_full_unstemmed | Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title_short | Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence |
title_sort | task state representations in vmpfc mediate relevant and irrelevant value signals and their behavioral influence |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232498/ https://www.ncbi.nlm.nih.gov/pubmed/37258534 http://dx.doi.org/10.1038/s41467-023-38709-w |
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