Increasing maternal age associates with lower placental CPT1B mRNA expression and acylcarnitines, particularly in overweight women

Older pregnant women have increased risks of complications including gestational diabetes and stillbirth. Carnitine palmitoyl transferase (CPT) expression declines with age in several tissues and is linked with poorer metabolic health. Mitochondrial CPTs catalyze acylcarnitine synthesis, which facil...

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Detalles Bibliográficos
Autores principales: Yong, Hannah E. J., Watkins, Oliver C., Mah, Tania K. L., Cracknell-Hazra, Victoria K. B., Pillai, Reshma Appukuttan, Selvam, Preben, Islam, Mohammad O., Sharma, Neha, Cazenave-Gassiot, Amaury, Bendt, Anne K., Wenk, Markus R., Godfrey, Keith M., Lewis, Rohan M., Chan, Shiao-Yng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232777/
https://www.ncbi.nlm.nih.gov/pubmed/37275238
http://dx.doi.org/10.3389/fphys.2023.1166827

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