An update on the development of novel antifungal agents for eumycetoma

Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being...

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Autores principales: Chandler, David J., Bonifaz, Alexandro, van de Sande, Wendy W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232793/
https://www.ncbi.nlm.nih.gov/pubmed/37274106
http://dx.doi.org/10.3389/fphar.2023.1165273
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author Chandler, David J.
Bonifaz, Alexandro
van de Sande, Wendy W. J.
author_facet Chandler, David J.
Bonifaz, Alexandro
van de Sande, Wendy W. J.
author_sort Chandler, David J.
collection PubMed
description Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead.
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spelling pubmed-102327932023-06-02 An update on the development of novel antifungal agents for eumycetoma Chandler, David J. Bonifaz, Alexandro van de Sande, Wendy W. J. Front Pharmacol Pharmacology Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead. Frontiers Media S.A. 2023-05-18 /pmc/articles/PMC10232793/ /pubmed/37274106 http://dx.doi.org/10.3389/fphar.2023.1165273 Text en Copyright © 2023 Chandler, Bonifaz and van de Sande. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Chandler, David J.
Bonifaz, Alexandro
van de Sande, Wendy W. J.
An update on the development of novel antifungal agents for eumycetoma
title An update on the development of novel antifungal agents for eumycetoma
title_full An update on the development of novel antifungal agents for eumycetoma
title_fullStr An update on the development of novel antifungal agents for eumycetoma
title_full_unstemmed An update on the development of novel antifungal agents for eumycetoma
title_short An update on the development of novel antifungal agents for eumycetoma
title_sort update on the development of novel antifungal agents for eumycetoma
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232793/
https://www.ncbi.nlm.nih.gov/pubmed/37274106
http://dx.doi.org/10.3389/fphar.2023.1165273
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