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Single cell transcriptomics of bone marrow derived macrophages reveals Ccl5 as a biomarker of direct IFNAR-independent responses to DNA sensing

INTRODUCTION: The type I interferon (IFN) response is an innate immune program that mediates anti-viral, anti-cancer, auto-immune, auto-inflammatory, and sterile injury responses. Bone marrow derived macrophages (BMDMs) are commonly used to model macrophage type I IFN responses, but the use of bulk...

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Detalles Bibliográficos
Autores principales:	McCarty, Emily, Yu, Justin, Ninh, Van K., Calcagno, David M., Lee, Jodi, King, Kevin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232813/ https://www.ncbi.nlm.nih.gov/pubmed/37275883 http://dx.doi.org/10.3389/fimmu.2023.1199730

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