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Impact of peptide:HLA complex stability for the identification of SARS-CoV-2-specific CD8(+)T cells

Induction of a lasting protective immune response is dependent on presentation of epitopes to patrolling T cells through the HLA complex. While peptide:HLA (pHLA) complex affinity alone is widely exploited for epitope selection, we demonstrate that including the pHLA complex stability as a selection...

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Detalles Bibliográficos
Autores principales:	Lie-Andersen, Olivia, Hübbe, Mie Linder, Subramaniam, Krishanthi, Steen-Jensen, Daniel, Bergmann, Ann Christina, Justesen, Daniel, Holmström, Morten Orebo, Turtle, Lance, Justesen, Sune, Lança, Telma, Hansen, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232890/ https://www.ncbi.nlm.nih.gov/pubmed/37275886 http://dx.doi.org/10.3389/fimmu.2023.1151659

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