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Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency

Pulmonary sarcomatoid carcinomas (PSCA) are a rare subset of Non-Squamous-Cell Lung Carcinoma (NSCLC), the most common pathological subtype of lung cancers which are the most common malignancy in the world. These rarest of rare tumours may have gastrointestinal metastasis and present as an acute abd...

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Detalles Bibliográficos
Autores principales: Joacquim, Moses Amarjothi, Bhat, Nadeem, Kulkarni, Nikhil, Coup, Andrew, Dharmavaram, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233168/
https://www.ncbi.nlm.nih.gov/pubmed/37273401
http://dx.doi.org/10.7759/cureus.38414
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author Joacquim, Moses Amarjothi
Bhat, Nadeem
Kulkarni, Nikhil
Coup, Andrew
Dharmavaram, Sridhar
author_facet Joacquim, Moses Amarjothi
Bhat, Nadeem
Kulkarni, Nikhil
Coup, Andrew
Dharmavaram, Sridhar
author_sort Joacquim, Moses Amarjothi
collection PubMed
description Pulmonary sarcomatoid carcinomas (PSCA) are a rare subset of Non-Squamous-Cell Lung Carcinoma (NSCLC), the most common pathological subtype of lung cancers which are the most common malignancy in the world. These rarest of rare tumours may have gastrointestinal metastasis and present as an acute abdominal surgical emergency with bowel obstruction or bleeding, as in our patient, who did not have a diagnosis of lung cancer till then. Use of novel immunohistochemistry markers like thyroid transcription factor-1 (TTF-1) may help diagnose the site of the primary tumour with accuracy in this clinical setting. Further evaluation of these patients with positron emission tomography (PET) scans helps determine the tumour burden and degree of dissemination. The aim of this article is to emphasize this rare presentation which may be unsuspected as a cause of bowel obstruction by surgical teams on the acute surgical take due to its rarity. It is vital that nihilism is avoided in these patients as a subset of these patients can still be offered curative metastectomy and treatment of the primary tumour with reasonable outcomes.
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spelling pubmed-102331682023-06-02 Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency Joacquim, Moses Amarjothi Bhat, Nadeem Kulkarni, Nikhil Coup, Andrew Dharmavaram, Sridhar Cureus Gastroenterology Pulmonary sarcomatoid carcinomas (PSCA) are a rare subset of Non-Squamous-Cell Lung Carcinoma (NSCLC), the most common pathological subtype of lung cancers which are the most common malignancy in the world. These rarest of rare tumours may have gastrointestinal metastasis and present as an acute abdominal surgical emergency with bowel obstruction or bleeding, as in our patient, who did not have a diagnosis of lung cancer till then. Use of novel immunohistochemistry markers like thyroid transcription factor-1 (TTF-1) may help diagnose the site of the primary tumour with accuracy in this clinical setting. Further evaluation of these patients with positron emission tomography (PET) scans helps determine the tumour burden and degree of dissemination. The aim of this article is to emphasize this rare presentation which may be unsuspected as a cause of bowel obstruction by surgical teams on the acute surgical take due to its rarity. It is vital that nihilism is avoided in these patients as a subset of these patients can still be offered curative metastectomy and treatment of the primary tumour with reasonable outcomes. Cureus 2023-05-01 /pmc/articles/PMC10233168/ /pubmed/37273401 http://dx.doi.org/10.7759/cureus.38414 Text en Copyright © 2023, Joacquim et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Joacquim, Moses Amarjothi
Bhat, Nadeem
Kulkarni, Nikhil
Coup, Andrew
Dharmavaram, Sridhar
Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title_full Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title_fullStr Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title_full_unstemmed Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title_short Sarcomatoid Carcinoma of the Lung With Gastrointestinal Metastasis Causing Small Intestinal Obstruction: A Rare Case of Acute Surgical Emergency
title_sort sarcomatoid carcinoma of the lung with gastrointestinal metastasis causing small intestinal obstruction: a rare case of acute surgical emergency
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233168/
https://www.ncbi.nlm.nih.gov/pubmed/37273401
http://dx.doi.org/10.7759/cureus.38414
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