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Electromagnetic deactivation spectroscopy of human coronavirus 229E

An investigation of the deactivation of pathogens using electromagnetic waves in the microwave region of the spectrum is achieved using custom-built waveguide structures. The waveguides feature sub-wavelength gratings to allow the integration of an air cooling system without disturbing the internal...

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Autores principales: Banting, Hayden, Goode, Ian, Flores, Carla E. Gallardo, Colpitts, Che C., Saavedra, Carlos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233187/
https://www.ncbi.nlm.nih.gov/pubmed/37264167
http://dx.doi.org/10.1038/s41598-023-36030-6
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author Banting, Hayden
Goode, Ian
Flores, Carla E. Gallardo
Colpitts, Che C.
Saavedra, Carlos E.
author_facet Banting, Hayden
Goode, Ian
Flores, Carla E. Gallardo
Colpitts, Che C.
Saavedra, Carlos E.
author_sort Banting, Hayden
collection PubMed
description An investigation of the deactivation of pathogens using electromagnetic waves in the microwave region of the spectrum is achieved using custom-built waveguide structures. The waveguides feature sub-wavelength gratings to allow the integration of an air cooling system without disturbing the internal propagating fields. The waveguides are tapered to accommodate an experimental sample internally with sufficient surrounding airflow. The proposed methodology allows for precise control over power densities due to the well-defined fundamental mode excited in each waveguide, in addition to temperature control of the sample due to microwave exposure over time. Human coronavirus (HCoV-229E) is investigated over the 0–40 GHz range, where a peak 3-log viral reduction is observed in the 15.0–19.5 GHz sub-band. We conclude HCoV-229E has an intrinsic resonance in this range, where nonthermal structure damage is optimal through the structure-resonant energy transfer effect.
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spelling pubmed-102331872023-06-01 Electromagnetic deactivation spectroscopy of human coronavirus 229E Banting, Hayden Goode, Ian Flores, Carla E. Gallardo Colpitts, Che C. Saavedra, Carlos E. Sci Rep Article An investigation of the deactivation of pathogens using electromagnetic waves in the microwave region of the spectrum is achieved using custom-built waveguide structures. The waveguides feature sub-wavelength gratings to allow the integration of an air cooling system without disturbing the internal propagating fields. The waveguides are tapered to accommodate an experimental sample internally with sufficient surrounding airflow. The proposed methodology allows for precise control over power densities due to the well-defined fundamental mode excited in each waveguide, in addition to temperature control of the sample due to microwave exposure over time. Human coronavirus (HCoV-229E) is investigated over the 0–40 GHz range, where a peak 3-log viral reduction is observed in the 15.0–19.5 GHz sub-band. We conclude HCoV-229E has an intrinsic resonance in this range, where nonthermal structure damage is optimal through the structure-resonant energy transfer effect. Nature Publishing Group UK 2023-06-01 /pmc/articles/PMC10233187/ /pubmed/37264167 http://dx.doi.org/10.1038/s41598-023-36030-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Banting, Hayden
Goode, Ian
Flores, Carla E. Gallardo
Colpitts, Che C.
Saavedra, Carlos E.
Electromagnetic deactivation spectroscopy of human coronavirus 229E
title Electromagnetic deactivation spectroscopy of human coronavirus 229E
title_full Electromagnetic deactivation spectroscopy of human coronavirus 229E
title_fullStr Electromagnetic deactivation spectroscopy of human coronavirus 229E
title_full_unstemmed Electromagnetic deactivation spectroscopy of human coronavirus 229E
title_short Electromagnetic deactivation spectroscopy of human coronavirus 229E
title_sort electromagnetic deactivation spectroscopy of human coronavirus 229e
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233187/
https://www.ncbi.nlm.nih.gov/pubmed/37264167
http://dx.doi.org/10.1038/s41598-023-36030-6
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