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Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration

Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R) (also known as ATGL). PEDF-R exhibits phospholipase activity that mediates the neurotrophic action of its ligand PEDF. Because phospholipids...

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Detalles Bibliográficos
Autores principales:	Bernardo-Colón, Alexandra, Dong, Lijin, Abu-Asab, Mones, Brush, Richard S., Agbaga, Martin-Paul, Becerra, S. Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233210/ https://www.ncbi.nlm.nih.gov/pubmed/36934843 http://dx.doi.org/10.1016/j.jlr.2023.100358

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