Cargando…

Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer’s disease

Dysexecutive Alzheimer’s disease (dAD) manifests as a progressive dysexecutive syndrome without prominent behavioral features, and previous studies suggest clinico-radiological heterogeneity within this syndrome. We uncovered this heterogeneity using unsupervised machine learning in 52 dAD patients...

Descripción completa

Detalles Bibliográficos
Autores principales:	Corriveau-Lecavalier, Nick, Barnard, Leland R, Lee, Jeyeon, Dicks, Ellen, Botha, Hugo, Graff-Radford, Jonathan, Machulda, Mary M, Boeve, Bradley F, Knopman, David S, Lowe, Val J, Petersen, Ronald C, Jack, Jr, Clifford R, Jones, David T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233237/ https://www.ncbi.nlm.nih.gov/pubmed/36721911 http://dx.doi.org/10.1093/cercor/bhad017

Ejemplares similares

Default mode network failure and neurodegeneration across aging and amnestic and dysexecutive Alzheimer’s disease
por: Corriveau-Lecavalier, Nick, et al.
Publicado: (2023)

Progressive dysexecutive syndrome due to Alzheimer’s disease: a description of 55 cases and comparison to other phenotypes
por: Townley, Ryan A, et al.
Publicado: (2020)

Amyloid- and tau-PET imaging in a familial prion kindred
por: Jones, David T., et al.
Publicado: (2018)

(18)F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus
por: Townley, Ryan A., et al.
Publicado: (2018)

A robust biomarker of large-scale network failure in Alzheimer's disease
por: Wiepert, Daniela A., et al.
Publicado: (2017)

Posterior cortical atrophy phenotypic heterogeneity revealed by decoding (18)F-FDG-PET
por: Townley, Ryan A, et al.
Publicado: (2021)

Artificial intelligence and the aging mind
por: Lee, Jeyeon, et al.
Publicado: (2023)

Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging
por: Vemuri, Prashanthi, et al.
Publicado: (2019)

Multiple aetiologies of the progressive dysexecutive syndrome and the importance of biomarkers
por: Jones, David T
Publicado: (2020)

Dysexecutive Behavior in First-Episode Schizophrenia
por: Orellana, Gricel, et al.
Publicado: (2022)

A computational model of neurodegeneration in Alzheimer’s disease
por: Jones, D., et al.
Publicado: (2022)

Longitudinal deterioration of white-matter integrity: heterogeneity in the ageing population
por: Poulakis, Konstantinos, et al.
Publicado: (2021)

Novel GRN mutation presenting as an aphasic dementia and evolving into corticobasal syndrome
por: Botha, Hugo, et al.
Publicado: (2017)

The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes
por: Jack, Clifford R, et al.
Publicado: (2019)

Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes
por: Marks, Jordan D., et al.
Publicado: (2021)

MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous
por: Josephs, Keith A., et al.
Publicado: (2020)

White matter abnormalities are key components of cerebrovascular disease impacting cognitive decline
por: Vemuri, Prashanthi, et al.
Publicado: (2021)

Temporal Cortical Thickness and Cognitive Associations among Typical and Atypical Phenotypes of Alzheimer’s Disease
por: Butts, Alissa M., et al.
Publicado: (2022)

Relationship Between Risk Factors and Brain Reserve in Late Middle Age: Implications for Cognitive Aging
por: Neth, Bryan J., et al.
Publicado: (2020)

Longitudinal Tau Positron Emission Tomography in Dementia with Lewy Bodies
por: Chen, Qin, et al.
Publicado: (2022)

The Epidemiology and Clinical Manifestations of Dysexecutive Syndrome in Parkinson’s Disease
por: Ceravolo, Roberto, et al.
Publicado: (2012)

Prevalence and Clinical Correlates of Poststroke Behavioral Dysexecutive Syndrome
por: Tang, Wai Kwong, et al.
Publicado: (2019)

Coping with brain amyloid: genetic heterogeneity and cognitive resilience to Alzheimer’s pathophysiology
por: Ramanan, Vijay K., et al.
Publicado: (2021)

FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD
por: Kantarci, Kejal, et al.
Publicado: (2021)

Altered within- and between-network functional connectivity in atypical Alzheimer’s disease
por: Singh, Neha Atulkumar, et al.
Publicado: (2023)

Relationships between β-amyloid and tau in an elderly population: An accelerated failure time model
por: Therneau, Terry M., et al.
Publicado: (2021)

Cascading network failure across the Alzheimer’s disease spectrum
por: Jones, David T., et al.
Publicado: (2016)

The Overlap Index as a Means of Evaluating Early Tau PET Signal Reliability
por: Lee, Jeyeon, et al.
Publicado: (2022)

(18)F‐AV‐1451 uptake differs between dementia with lewy bodies and posterior cortical atrophy
por: Nedelska, Zuzana, et al.
Publicado: (2019)

Association of Cerebrovascular Imaging Biomarkers, Depression, and Anxiety, with Mild Cognitive Impairment
por: Vassilaki, Maria, et al.
Publicado: (2023)

Association of Apolipoprotein E ɛ4, Educational Level, and Sex With Tau Deposition and Tau-Mediated Metabolic Dysfunction in Older Adults
por: Ramanan, Vijay K, et al.
Publicado: (2019)

Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease
por: Sintini, Irene, et al.
Publicado: (2019)

Associations of quantitative susceptibility mapping with Alzheimer’s disease clinical and imaging markers
por: Cogswell, Petrice M., et al.
Publicado: (2020)

Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET
por: Nedelska, Zuzana, et al.
Publicado: (2018)

NIA‐AA Alzheimer's Disease Framework: Clinical Characterization of Stages
por: Petersen, Ronald C., et al.
Publicado: (2021)

Distinct brain iron profiles associated with logopenic progressive aphasia and posterior cortical atrophy
por: Singh, Neha Atulkumar, et al.
Publicado: (2022)

Low eGFR is associated with dysexecutive and amnestic mild cognitive impairment
por: Zammit, Andrea R., et al.
Publicado: (2015)

Parkinsonian Patients with Deficits in the Dysexecutive Spectrum are Impaired on Theory of Mind Tasks
por: Costa, Alberto, et al.
Publicado: (2013)

Dysexecutive mild cognitive impairment associated to frontal atrophy: Case report
por: Balthazar, Marcio Luiz Figueredo, et al.
Publicado: (2008)

Dysexecutive syndrome in amnesic mild cognitive impairment: a multicenter study
por: Blanco Martín, E., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4c0japno858p0hk4muu8rf1m3c