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Fuel oxidation under the control of mitochondrial shape and dynamics
How mitochondrial shape and substrate‐specific metabolism are related has been a difficult question to address. Here, new work by Ngo et al (2023) reports that mitochondrial shape—long versus fragmented—determines the activity of β‐oxidation of long‐chain fatty acids, supporting a novel role for mit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233371/ https://www.ncbi.nlm.nih.gov/pubmed/37154272 http://dx.doi.org/10.15252/embj.2023114129 |
| Sumario: | How mitochondrial shape and substrate‐specific metabolism are related has been a difficult question to address. Here, new work by Ngo et al (2023) reports that mitochondrial shape—long versus fragmented—determines the activity of β‐oxidation of long‐chain fatty acids, supporting a novel role for mitochondrial fission products as β‐oxidation hubs. |
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