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Fuel oxidation under the control of mitochondrial shape and dynamics
How mitochondrial shape and substrate‐specific metabolism are related has been a difficult question to address. Here, new work by Ngo et al (2023) reports that mitochondrial shape—long versus fragmented—determines the activity of β‐oxidation of long‐chain fatty acids, supporting a novel role for mit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233371/ https://www.ncbi.nlm.nih.gov/pubmed/37154272 http://dx.doi.org/10.15252/embj.2023114129 |
| _version_ | 1785052219940274176 |
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| author | Seifert, Erin L Hajnóczky, György |
| author_facet | Seifert, Erin L Hajnóczky, György |
| author_sort | Seifert, Erin L |
| collection | PubMed |
| description | How mitochondrial shape and substrate‐specific metabolism are related has been a difficult question to address. Here, new work by Ngo et al (2023) reports that mitochondrial shape—long versus fragmented—determines the activity of β‐oxidation of long‐chain fatty acids, supporting a novel role for mitochondrial fission products as β‐oxidation hubs. |
| format | Online Article Text |
| id | pubmed-10233371 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102333712023-06-02 Fuel oxidation under the control of mitochondrial shape and dynamics Seifert, Erin L Hajnóczky, György EMBO J News & Views How mitochondrial shape and substrate‐specific metabolism are related has been a difficult question to address. Here, new work by Ngo et al (2023) reports that mitochondrial shape—long versus fragmented—determines the activity of β‐oxidation of long‐chain fatty acids, supporting a novel role for mitochondrial fission products as β‐oxidation hubs. John Wiley and Sons Inc. 2023-05-08 /pmc/articles/PMC10233371/ /pubmed/37154272 http://dx.doi.org/10.15252/embj.2023114129 Text en © 2023 The Authors. Published under the terms of the CC BY NC ND 4.0 license. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | News & Views Seifert, Erin L Hajnóczky, György Fuel oxidation under the control of mitochondrial shape and dynamics |
| title | Fuel oxidation under the control of mitochondrial shape and dynamics |
| title_full | Fuel oxidation under the control of mitochondrial shape and dynamics |
| title_fullStr | Fuel oxidation under the control of mitochondrial shape and dynamics |
| title_full_unstemmed | Fuel oxidation under the control of mitochondrial shape and dynamics |
| title_short | Fuel oxidation under the control of mitochondrial shape and dynamics |
| title_sort | fuel oxidation under the control of mitochondrial shape and dynamics |
| topic | News & Views |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233371/ https://www.ncbi.nlm.nih.gov/pubmed/37154272 http://dx.doi.org/10.15252/embj.2023114129 |
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