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Dysregulation in IFN-γ signaling and response: the barricade to tumor immunotherapy

Interferon-gamma (IFN-γ) has been identified as a crucial factor in determining the responsiveness to immunotherapy. Produced primarily by natural killer (NK) and T cells, IFN-γ promotes activation, maturation, proliferation, cytokine expression, and effector function in immune cells, while simultan...

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Detalles Bibliográficos
Autores principales: Han, Jiashu, Wu, Mengwei, Liu, Ziwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233742/
https://www.ncbi.nlm.nih.gov/pubmed/37275859
http://dx.doi.org/10.3389/fimmu.2023.1190333

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