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Dysregulation in IFN-γ signaling and response: the barricade to tumor immunotherapy
Interferon-gamma (IFN-γ) has been identified as a crucial factor in determining the responsiveness to immunotherapy. Produced primarily by natural killer (NK) and T cells, IFN-γ promotes activation, maturation, proliferation, cytokine expression, and effector function in immune cells, while simultan...
Autores principales: | Han, Jiashu, Wu, Mengwei, Liu, Ziwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233742/ https://www.ncbi.nlm.nih.gov/pubmed/37275859 http://dx.doi.org/10.3389/fimmu.2023.1190333 |
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