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Efficacy and safety of ripretinib in Chinese patients with advanced gastrointestinal stromal tumors: a real-world, multicenter, observational study

INTRODUCTION: Mutations in KIT proto-oncogene, receptor tyrosine kinase (KIT) and platelet-derived growth factor receptor-α (PDGFRA) render the available tyrosine kinase inhibitors (TKI) ineffective in treating advanced gastrointestinal stromal tumors (GIST). Ripretinib, a broad-spectrum switch-cont...

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Detalles Bibliográficos
Autores principales: Yang, Weili, Qian, Haoran, Yang, Litao, Wang, Pengfei, Qian, Hailong, Chu, Binbin, Liu, Zhuo, Sun, Jingyu, Wu, Dan, Sun, Lifeng, Zhou, Wenqiang, Hu, Jingwei, Chen, Xiaolei, Shou, Chunhui, Ruan, Lingxiang, Zhang, Yunyun, Yu, Jiren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233743/
https://www.ncbi.nlm.nih.gov/pubmed/37274264
http://dx.doi.org/10.3389/fonc.2023.1180795