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5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis

[Image: see text] Previous studies have indicated that the pathogenesis of amyotrophic lateral sclerosis (ALS) is closely linked to 5-hydroxytryptamine (5-HT). To investigate this further, we administered 5-HT receptor antagonists to SOD1*G93A transgenic (ALS mouse model) and wide-type mice. This in...

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Detalles Bibliográficos
Autores principales: Jiang, Shi-Shi, Gong, Meng-Ni, Rao, Wei, Chai, Wen, Chen, Wen-Zhi, Zhang, Xiong, Nie, Hong-Bing, Xu, Ren-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233787/
https://www.ncbi.nlm.nih.gov/pubmed/36926731
http://dx.doi.org/10.4103/1673-5374.367929