GPR43 stimulation on TCRαβ(+) intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity

INTRODUCTION: Gut microbiota plays a critical role in the regulation of immune homeostasis. Accordingly, several autoimmune disorders have been associated with dysbiosis in the gut microbiota. Notably, the dysbiosis associated with central nervous system (CNS) autoimmunity involves a substantial red...

Descripción completa

Detalles Bibliográficos
Autores principales: Prado, Carolina, Espinoza, Alexandra, Martínez-Hernández, J. Eduardo, Petrosino, Joseph, Riquelme, Erick, Martin, Alberto J. M., Pacheco, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233874/
https://www.ncbi.nlm.nih.gov/pubmed/37264394
http://dx.doi.org/10.1186/s12974-023-02815-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233874/
https://www.ncbi.nlm.nih.gov/pubmed/37264394
http://dx.doi.org/10.1186/s12974-023-02815-9

Ejemplares similares