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GPR43 stimulation on TCRαβ(+) intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity
INTRODUCTION: Gut microbiota plays a critical role in the regulation of immune homeostasis. Accordingly, several autoimmune disorders have been associated with dysbiosis in the gut microbiota. Notably, the dysbiosis associated with central nervous system (CNS) autoimmunity involves a substantial red...
Autores principales: | Prado, Carolina, Espinoza, Alexandra, Martínez-Hernández, J. Eduardo, Petrosino, Joseph, Riquelme, Erick, Martin, Alberto J. M., Pacheco, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233874/ https://www.ncbi.nlm.nih.gov/pubmed/37264394 http://dx.doi.org/10.1186/s12974-023-02815-9 |
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