Cargando…
A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection
PURPOSE: To observe long-term prognosis of anterior segment ischemia (ASI) following hyaluronic acid (HA) injection, propose a severity grading system for ASI and a predictive model for phthisis bulbi (PB) based on long-term secretion dysfunction of ciliary process. METHODS: This is a retrospective...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233880/ https://www.ncbi.nlm.nih.gov/pubmed/37259051 http://dx.doi.org/10.1186/s12886-023-02992-4 |
_version_ | 1785052357643468800 |
---|---|
author | Si, Shancheng Su, Wei Wang, Lei Ji, Yicong Chen, Anming Hu, Yuntao |
author_facet | Si, Shancheng Su, Wei Wang, Lei Ji, Yicong Chen, Anming Hu, Yuntao |
author_sort | Si, Shancheng |
collection | PubMed |
description | PURPOSE: To observe long-term prognosis of anterior segment ischemia (ASI) following hyaluronic acid (HA) injection, propose a severity grading system for ASI and a predictive model for phthisis bulbi (PB) based on long-term secretion dysfunction of ciliary process. METHODS: This is a retrospective case–control study. All enrolled 20 patients were divided into two groups and followed for at least 6 months to observe the formation and transformation characteristics of ASI and long-term prognosis based on the degrees of ciliary function damage. RESULTS: The severity of ASI following HA injection could be subdivided into 4 grades according to the degrees of ciliary function damage, comprising ASI grades 0, 1, 2 and 3. In 20 patients, ophthalmoplegia at 1-month follow-up, ASI within 1 month, ASI at 1-month follow-up, hypotony within 6 months were all significantly more common in study group than in control group (60% vs. 0%, P = 0.011; 100% vs. 20%, P = 0.001; 100% vs. 0%, P < 0.001; 80% vs. 0%, P = 0.001, respectively). Sensitivity, specificity and the area under the receiver operating characteristic curve (AUC) for predicting subsequent PB at 2-year follow-up through the co-occurrence of ophthalmoplegia at 1-month follow-up and hypotony within 6 months was 100%, 100% and 1.00, respectively. CONCLUSIONS: The new grading system for ASI and novel predictive model for PB we proposed could predict the long-term prognosis and probability of subsequent PB due to ASI following HA injection through several dynamic assessments within 6 months. LEVEL OF EVIDENCE: Level IV, observational prognostic study. |
format | Online Article Text |
id | pubmed-10233880 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-102338802023-06-02 A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection Si, Shancheng Su, Wei Wang, Lei Ji, Yicong Chen, Anming Hu, Yuntao BMC Ophthalmol Research Article PURPOSE: To observe long-term prognosis of anterior segment ischemia (ASI) following hyaluronic acid (HA) injection, propose a severity grading system for ASI and a predictive model for phthisis bulbi (PB) based on long-term secretion dysfunction of ciliary process. METHODS: This is a retrospective case–control study. All enrolled 20 patients were divided into two groups and followed for at least 6 months to observe the formation and transformation characteristics of ASI and long-term prognosis based on the degrees of ciliary function damage. RESULTS: The severity of ASI following HA injection could be subdivided into 4 grades according to the degrees of ciliary function damage, comprising ASI grades 0, 1, 2 and 3. In 20 patients, ophthalmoplegia at 1-month follow-up, ASI within 1 month, ASI at 1-month follow-up, hypotony within 6 months were all significantly more common in study group than in control group (60% vs. 0%, P = 0.011; 100% vs. 20%, P = 0.001; 100% vs. 0%, P < 0.001; 80% vs. 0%, P = 0.001, respectively). Sensitivity, specificity and the area under the receiver operating characteristic curve (AUC) for predicting subsequent PB at 2-year follow-up through the co-occurrence of ophthalmoplegia at 1-month follow-up and hypotony within 6 months was 100%, 100% and 1.00, respectively. CONCLUSIONS: The new grading system for ASI and novel predictive model for PB we proposed could predict the long-term prognosis and probability of subsequent PB due to ASI following HA injection through several dynamic assessments within 6 months. LEVEL OF EVIDENCE: Level IV, observational prognostic study. BioMed Central 2023-05-31 /pmc/articles/PMC10233880/ /pubmed/37259051 http://dx.doi.org/10.1186/s12886-023-02992-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Si, Shancheng Su, Wei Wang, Lei Ji, Yicong Chen, Anming Hu, Yuntao A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title | A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title_full | A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title_fullStr | A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title_full_unstemmed | A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title_short | A novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
title_sort | novel predictive model for phthisis bulbi following facial hyaluronic acid cosmetic injection |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233880/ https://www.ncbi.nlm.nih.gov/pubmed/37259051 http://dx.doi.org/10.1186/s12886-023-02992-4 |
work_keys_str_mv | AT sishancheng anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT suwei anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT wanglei anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT jiyicong anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT chenanming anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT huyuntao anovelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT sishancheng novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT suwei novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT wanglei novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT jiyicong novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT chenanming novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection AT huyuntao novelpredictivemodelforphthisisbulbifollowingfacialhyaluronicacidcosmeticinjection |