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Looking for answers far away from the soma—the (un)known axonal functions of TDP-43, and their contribution to early NMJ disruption in ALS

Axon degeneration and Neuromuscular Junction (NMJ) disruption are key pathologies in the fatal neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). Despite accumulating evidence that axons and NMJs are impacted at a very early stage of the disease, current knowledge about the mechanisms le...

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Detalles Bibliográficos
Autores principales:	Ionescu, Ariel, Altman, Topaz, Perlson, Eran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233987/ https://www.ncbi.nlm.nih.gov/pubmed/37259156 http://dx.doi.org/10.1186/s13024-023-00623-6

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