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Minocycline protects against microgliopathy in a Csf1r haplo-insufficient mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)

BACKGROUND: Mutations in colony-stimulating factor 1 receptor (CSF1R) are known to cause adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), which has been recently demonstrated as a primary microgliopathy characterized by cognitive impairment. Although the molecular mec...

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Detalles Bibliográficos
Autores principales:	Li, Xin, Hu, Banglian, Guan, Xiaoyan, Wang, Ziwei, Zhou, Yuhang, Sun, Hao, Zhang, Xian, Li, Yanfang, Huang, Xiaohua, Zhao, Yingjun, Wang, Xin, Xu, Huaxi, Zhang, Yun-Wu, Wang, Zhanxiang, Zheng, Honghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234026/ https://www.ncbi.nlm.nih.gov/pubmed/37259140 http://dx.doi.org/10.1186/s12974-023-02774-1

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