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Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models

Aminoacyl-tRNA synthetases (ARSs) play an essential role in protein synthesis, being responsible for ligating tRNA molecules to their corresponding amino acids in a reaction known as ‘tRNA aminoacylation’. Separate ARSs carry out the aminoacylation reaction in the cytosol and in mitochondria, and mu...

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Detalles Bibliográficos
Autores principales: Kalotay, Elizabeth, Klugmann, Matthias, Housley, Gary D., Fröhlich, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234151/
https://www.ncbi.nlm.nih.gov/pubmed/37274211
http://dx.doi.org/10.3389/fnins.2023.1182845

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