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COVID-19 SIR model: Bifurcation analysis and optimal control
This paper proposes a SIR epidemic model with vital dynamics to control or eliminate the spread of the COVID-19 epidemic considering the constant population, saturated treatment, and direct–indirect transmission rate of the model. We demonstrate positivity, boundness and calculate the disease-free e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234369/ http://dx.doi.org/10.1016/j.rico.2023.100246 |
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author | Ahmed, Mostak Khan, Md. Harun-Or-Rashid Alam Sarker, Md. Manirul |
author_facet | Ahmed, Mostak Khan, Md. Harun-Or-Rashid Alam Sarker, Md. Manirul |
author_sort | Ahmed, Mostak |
collection | PubMed |
description | This paper proposes a SIR epidemic model with vital dynamics to control or eliminate the spread of the COVID-19 epidemic considering the constant population, saturated treatment, and direct–indirect transmission rate of the model. We demonstrate positivity, boundness and calculate the disease-free equilibrium point and basic reproduction number from the model. We use the Jacobian matrix and the Lyapunov function to analyze the local and global stability, respectively. It is observed that indirect infection increases the basic reproduction number and gives rise to multiple endemic diseases. We perform transcritical, forward, backward, and Hopf bifurcation analyses. We propose two control parameters (Use of face mask, hand sanitizer, social distancing, and vaccination) to minimize the spread of the coronavirus. We use Pontryagin’s maximum principle to solve the optimal control problem and demonstrate the results numerically. |
format | Online Article Text |
id | pubmed-10234369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Author(s). Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102343692023-06-01 COVID-19 SIR model: Bifurcation analysis and optimal control Ahmed, Mostak Khan, Md. Harun-Or-Rashid Alam Sarker, Md. Manirul Results in Control and Optimization Article This paper proposes a SIR epidemic model with vital dynamics to control or eliminate the spread of the COVID-19 epidemic considering the constant population, saturated treatment, and direct–indirect transmission rate of the model. We demonstrate positivity, boundness and calculate the disease-free equilibrium point and basic reproduction number from the model. We use the Jacobian matrix and the Lyapunov function to analyze the local and global stability, respectively. It is observed that indirect infection increases the basic reproduction number and gives rise to multiple endemic diseases. We perform transcritical, forward, backward, and Hopf bifurcation analyses. We propose two control parameters (Use of face mask, hand sanitizer, social distancing, and vaccination) to minimize the spread of the coronavirus. We use Pontryagin’s maximum principle to solve the optimal control problem and demonstrate the results numerically. The Author(s). Published by Elsevier B.V. 2023-09 2023-06-01 /pmc/articles/PMC10234369/ http://dx.doi.org/10.1016/j.rico.2023.100246 Text en © 2023 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Ahmed, Mostak Khan, Md. Harun-Or-Rashid Alam Sarker, Md. Manirul COVID-19 SIR model: Bifurcation analysis and optimal control |
title | COVID-19 SIR model: Bifurcation analysis and optimal control |
title_full | COVID-19 SIR model: Bifurcation analysis and optimal control |
title_fullStr | COVID-19 SIR model: Bifurcation analysis and optimal control |
title_full_unstemmed | COVID-19 SIR model: Bifurcation analysis and optimal control |
title_short | COVID-19 SIR model: Bifurcation analysis and optimal control |
title_sort | covid-19 sir model: bifurcation analysis and optimal control |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234369/ http://dx.doi.org/10.1016/j.rico.2023.100246 |
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