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Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection

Mitochondrial DNA heteroplasmy samples can shed light on vital developmental and genetic processes shaping mitochondrial DNA populations. The sample means and sample variance of a set of heteroplasmy observations are typically used both to estimate bottleneck sizes and to perform fits to the theoret...

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Detalles Bibliográficos
Autores principales:	Giannakis, Konstantinos, Broz, Amanda K, Sloan, Daniel B, Johnston, Iain G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234379/ https://www.ncbi.nlm.nih.gov/pubmed/36951404 http://dx.doi.org/10.1093/g3journal/jkad068

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