A spike-targeting bispecific T cell engager strategy provides dual layer protection against SARS-CoV-2 infection in vivo

Neutralizing antibodies exert a potent inhibitory effect on viral entry; however, they are less effective in therapeutic models than in prophylactic models, presumably because of their limited efficacy in eliminating virus-producing cells via Fc-mediated cytotoxicity. Herein, we present a SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Li, Fanlin, Xu, Wei, Zhang, Xiaoqing, Wang, Wanting, Su, Shan, Han, Ping, Wang, Haiyong, Xu, Yanqin, Li, Min, Fan, Lilv, Zhang, Huihui, Dai, Qiang, Lin, Hao, Qi, Xinyue, Liang, Jie, Wang, Xin, Jiang, Shibo, Xie, Youhua, Lu, Lu, Yang, Xuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234585/
https://www.ncbi.nlm.nih.gov/pubmed/37264086
http://dx.doi.org/10.1038/s42003-023-04955-3

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