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The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over

OBJECTIVE: For elderly patients aged ≥75 with esophageal cancer, whether surgical treatment is safe and effective and whether it is feasible to use a relatively radical “no tube, no fasting” fast-track recovery protocol remain topics of debate. We conducted a retrospective analysis to shed light on...

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Autores principales: Xing, Wenqun, Liu, Xianben, Miao, Peng, Hao, Wentao, Li, Keting, Wang, Hao, Zheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234604/
https://www.ncbi.nlm.nih.gov/pubmed/37274262
http://dx.doi.org/10.3389/fonc.2023.1144047
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author Xing, Wenqun
Liu, Xianben
Miao, Peng
Hao, Wentao
Li, Keting
Wang, Hao
Zheng, Yan
author_facet Xing, Wenqun
Liu, Xianben
Miao, Peng
Hao, Wentao
Li, Keting
Wang, Hao
Zheng, Yan
author_sort Xing, Wenqun
collection PubMed
description OBJECTIVE: For elderly patients aged ≥75 with esophageal cancer, whether surgical treatment is safe and effective and whether it is feasible to use a relatively radical “no tube, no fasting” fast-track recovery protocol remain topics of debate. We conducted a retrospective analysis to shed light on these two questions. METHODS: We retrospectively collected the data of patients who underwent McKeown minimally invasive esophagectomy (MIE) combined with early oral feeding (EOF) on postoperative day 1 between April 2015 and December 2017 at Medical Group 1, Ward 1, Department of Thoracic Surgery of our hospital. Preoperative characteristics, postoperative complications, operation time, intraoperative blood loss, duration of anastomotic leakage (day), hospital stay, and survival were evaluated. RESULTS: Twenty-three elderly patients with esophageal cancer underwent surgery with EOF. No significant difference was observed in intraoperative measures. The incidence of postoperative complications was 34.8% (8/23). Two patients (8.7%) were terminated early during the analysis of the feasibility of EOF. For all 23 patients, the mean hospital stay was 11.4 (5-42) days, and the median survival was 51 months. CONCLUSION: Patients aged ≥75 with resectable esophageal cancer can achieve long-term survival with active surgical treatment. Moreover, the “no tube, no fasting” fast-track recovery protocol is safe and feasible for elderly patients.
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spelling pubmed-102346042023-06-02 The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over Xing, Wenqun Liu, Xianben Miao, Peng Hao, Wentao Li, Keting Wang, Hao Zheng, Yan Front Oncol Oncology OBJECTIVE: For elderly patients aged ≥75 with esophageal cancer, whether surgical treatment is safe and effective and whether it is feasible to use a relatively radical “no tube, no fasting” fast-track recovery protocol remain topics of debate. We conducted a retrospective analysis to shed light on these two questions. METHODS: We retrospectively collected the data of patients who underwent McKeown minimally invasive esophagectomy (MIE) combined with early oral feeding (EOF) on postoperative day 1 between April 2015 and December 2017 at Medical Group 1, Ward 1, Department of Thoracic Surgery of our hospital. Preoperative characteristics, postoperative complications, operation time, intraoperative blood loss, duration of anastomotic leakage (day), hospital stay, and survival were evaluated. RESULTS: Twenty-three elderly patients with esophageal cancer underwent surgery with EOF. No significant difference was observed in intraoperative measures. The incidence of postoperative complications was 34.8% (8/23). Two patients (8.7%) were terminated early during the analysis of the feasibility of EOF. For all 23 patients, the mean hospital stay was 11.4 (5-42) days, and the median survival was 51 months. CONCLUSION: Patients aged ≥75 with resectable esophageal cancer can achieve long-term survival with active surgical treatment. Moreover, the “no tube, no fasting” fast-track recovery protocol is safe and feasible for elderly patients. Frontiers Media S.A. 2023-05-18 /pmc/articles/PMC10234604/ /pubmed/37274262 http://dx.doi.org/10.3389/fonc.2023.1144047 Text en Copyright © 2023 Xing, Liu, Miao, Hao, Li, Wang and Zheng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Xing, Wenqun
Liu, Xianben
Miao, Peng
Hao, Wentao
Li, Keting
Wang, Hao
Zheng, Yan
The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title_full The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title_fullStr The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title_full_unstemmed The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title_short The feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
title_sort feasibility of a “no tube, no fasting” fast-track recovery protocol after esophagectomy for esophageal cancer patients aged 75 and over
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234604/
https://www.ncbi.nlm.nih.gov/pubmed/37274262
http://dx.doi.org/10.3389/fonc.2023.1144047
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