The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

Genes associated with increased susceptibility to multiple sclerosis (MS) have been identified, but their functions are incompletely understood. One of these genes codes for the RNA helicase DExD/H-Box Polypeptide 39B (DDX39B), which shows genetic and functional epistasis with interleukin-7 receptor...

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Detalles Bibliográficos
Autores principales: Hirano, Minato, Galarza-Muñoz, Gaddiel, Nagasawa, Chloe, Schott, Geraldine, Wang, Liuyang, Antonia, Alejandro L, Jain, Vaibhav, Yu, Xiaoying, Widen, Steven G, Briggs, Farren BS, Gregory, Simon G, Ko, Dennis C, Fagg, William S, Bradrick, Shelton, Garcia-Blanco, Mariano A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234631/
https://www.ncbi.nlm.nih.gov/pubmed/37261960
http://dx.doi.org/10.7554/eLife.76927

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