Identification of a Common Variant for Coronary Heart Disease at PDE1A Contributes to Individualized Treatment Goals and Risk Stratification of Cardiovascular Complications in Chinese Patients With Type 2 Diabetes

OBJECTIVE: In this study we aim to unravel genetic determinants of coronary heart disease (CHD) in type 2 diabetes (T2D) and explore their applications. RESEARCH DESIGN AND METHODS: We performed a two-stage genome-wide association study for CHD in Chinese patients with T2D (3,596 case and 8,898 cont...

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Detalles Bibliográficos
Autores principales: Tam, Claudia H.T., Lim, Cadmon K.P., Luk, Andrea O.Y., Shi, Mai, Man Cheung, Hoi, Ng, Alex C.W., Lee, Heung-man, Lau, Eric S.H., Fan, Baoqi, Jiang, Guozhi, Kong, Alice P.S., Ozaki, Risa, Chow, Elaine Y.K., Lee, Ka Fai, Siu, Shing Chung, Hui, Grace, Tsang, Chiu Chi, Lau, Kam Piu, Leung, Jenny Y.Y., Cheung, Elaine Y.N., Tsang, Man Wo, Kam, Grace, Lau, Ip Tim, Li, June K.Y., Yeung, Vincent T.F., Lau, Emmy, Lo, Stanley, Fung, Samuel, Cheng, Yuk Lun, Chow, Chun Chung, Fan, Xiaodan, Chan, Ting Fung, Yip, Kevin Y.L., Lok, Si, Yu, Weichuan, Tsui, Stephen K.W., Lan, Hui-yao, Szeto, Cheuk Chun, Tang, Nelson L.S., Tomlinson, Brian, Huang, Yu, Jenkins, Alicia J., Keech, Anthony, So, Wing-yee, Chan, Juliana C.N., Ma, Ronald C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234754/
https://www.ncbi.nlm.nih.gov/pubmed/37125963
http://dx.doi.org/10.2337/dc22-2331

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