Interleukin 1β triggers synaptic and memory deficits in Herpes simplex virus type-1-infected mice by downregulating the expression of synaptic plasticity-related genes via the epigenetic MeCP2/HDAC4 complex

Extensive research provides evidence that neuroinflammation underlies numerous brain disorders. However, the molecular mechanisms by which inflammatory mediators determine synaptic and cognitive dysfunction occurring in neurodegenerative diseases (e.g., Alzheimer’s disease) are far from being fully...

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Detalles Bibliográficos
Autores principales: Li Puma, Domenica Donatella, Colussi, Claudia, Bandiera, Bruno, Puliatti, Giulia, Rinaudo, Marco, Cocco, Sara, Paciello, Fabiola, Re, Agnese, Ripoli, Cristian, De Chiara, Giovanna, Bertozzi, Alessia, Palamara, Anna Teresa, Piacentini, Roberto, Grassi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234878/
https://www.ncbi.nlm.nih.gov/pubmed/37261502
http://dx.doi.org/10.1007/s00018-023-04817-5

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