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Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types
Homologous recombination deficiency (HRD) causes faulty double-strand break repair and is a prevalent cause of tumorigenesis. However, the incidence of HRD and its clinical significance in pan-cancer patients remain unknown. Using computational analysis of Single-nucleotide polymorphism array data f...
Autores principales: | Shi, Zhiwen, Chen, Bolin, Han, Xiao, Gu, Weiyue, Liang, Shuzhi, Wu, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235055/ https://www.ncbi.nlm.nih.gov/pubmed/37264024 http://dx.doi.org/10.1038/s41598-023-35092-w |
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