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Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types

Homologous recombination deficiency (HRD) causes faulty double-strand break repair and is a prevalent cause of tumorigenesis. However, the incidence of HRD and its clinical significance in pan-cancer patients remain unknown. Using computational analysis of Single-nucleotide polymorphism array data f...

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Detalles Bibliográficos
Autores principales: Shi, Zhiwen, Chen, Bolin, Han, Xiao, Gu, Weiyue, Liang, Shuzhi, Wu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235055/
https://www.ncbi.nlm.nih.gov/pubmed/37264024
http://dx.doi.org/10.1038/s41598-023-35092-w

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