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Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

The tumor immune composition influences prognosis and treatment sensitivity in lung cancer. The presence of effective adaptive immune responses is associated with increased clinical benefit after immune checkpoint blockers. Conversely, immunotherapy resistance can occur as a consequence of local T-c...

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Detalles Bibliográficos
Autores principales: Barrera, Cristian, Corredor, Germán, Viswanathan, Vidya Sankar, Ding, Ruiwen, Toro, Paula, Fu, Pingfu, Buzzy, Christina, Lu, Cheng, Velu, Priya, Zens, Philipp, Berezowska, Sabina, Belete, Merzu, Balli, David, Chang, Han, Baxi, Vipul, Syrigos, Konstantinos, Rimm, David L., Velcheti, Vamsidhar, Schalper, Kurt, Romero, Eduardo, Madabhushi, Anant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235089/
https://www.ncbi.nlm.nih.gov/pubmed/37264091
http://dx.doi.org/10.1038/s41698-023-00403-x