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APOEε4 and risk of Alzheimer’s disease – time to move forward

The inheritance of Apolipoprotein E4 (APOEε4) brings the highest genetic risk of Alzheimer’s disease (AD), arguably the highest genetic risk in human pathology. Since the discovery of the association, APOE protein isoforms have been at the center of tens of thousands of studies and reports. While, w...

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Detalles Bibliográficos
Autores principales: Lefterov, Iliya, Fitz, Nicholas F., Lu, Yi, Koldamova, Radosveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235508/
https://www.ncbi.nlm.nih.gov/pubmed/37274212
http://dx.doi.org/10.3389/fnins.2023.1195724