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Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis

Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung rec...

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Autores principales: Kitagawa, Norihiko, Shinkai, Masato, Asano, Fumio, Tsuzuki, Yukihiro, Mochizuki, Kyoko, Usui, Hidehito, Yagi, Yuma, Kawami, Akio, Okumura, Kazuyoshi, Yokosuka, Tomoko, Goto, Hiroaki, Nozawa, Kumiko, Tanaka, Mio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235763/
https://www.ncbi.nlm.nih.gov/pubmed/37274822
http://dx.doi.org/10.3389/fped.2023.1203212
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author Kitagawa, Norihiko
Shinkai, Masato
Asano, Fumio
Tsuzuki, Yukihiro
Mochizuki, Kyoko
Usui, Hidehito
Yagi, Yuma
Kawami, Akio
Okumura, Kazuyoshi
Yokosuka, Tomoko
Goto, Hiroaki
Nozawa, Kumiko
Tanaka, Mio
author_facet Kitagawa, Norihiko
Shinkai, Masato
Asano, Fumio
Tsuzuki, Yukihiro
Mochizuki, Kyoko
Usui, Hidehito
Yagi, Yuma
Kawami, Akio
Okumura, Kazuyoshi
Yokosuka, Tomoko
Goto, Hiroaki
Nozawa, Kumiko
Tanaka, Mio
author_sort Kitagawa, Norihiko
collection PubMed
description Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung recurrence rate after liver transplantation is still high. Therefore, transplantation should be avoided as much as possible. In cases of tumors in the right lobe of the liver, complete resection of the portal vein trunk may be possible by creating a Rex bypass, but with the original method, end-to-side anastomosis to the umbilical portal vein is difficult in small children. We report a case of a 2-year-old girl with hepatoblastoma in whom a Rex shunt was created by end-to-end anastomosing the recanalized umbilical vein to the portal vein stump with interposing a vein graft, and the right lobe was successfully resected along with the tumor.
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spelling pubmed-102357632023-06-03 Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis Kitagawa, Norihiko Shinkai, Masato Asano, Fumio Tsuzuki, Yukihiro Mochizuki, Kyoko Usui, Hidehito Yagi, Yuma Kawami, Akio Okumura, Kazuyoshi Yokosuka, Tomoko Goto, Hiroaki Nozawa, Kumiko Tanaka, Mio Front Pediatr Pediatrics Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung recurrence rate after liver transplantation is still high. Therefore, transplantation should be avoided as much as possible. In cases of tumors in the right lobe of the liver, complete resection of the portal vein trunk may be possible by creating a Rex bypass, but with the original method, end-to-side anastomosis to the umbilical portal vein is difficult in small children. We report a case of a 2-year-old girl with hepatoblastoma in whom a Rex shunt was created by end-to-end anastomosing the recanalized umbilical vein to the portal vein stump with interposing a vein graft, and the right lobe was successfully resected along with the tumor. Frontiers Media S.A. 2023-05-18 /pmc/articles/PMC10235763/ /pubmed/37274822 http://dx.doi.org/10.3389/fped.2023.1203212 Text en © 2023 Kitagawa, Shinkai, Asano, Tsuzuki, Mochizuki, Usui, Yagi, Kawami, Okumura, Yokosuka, Goto, Nozawa and Tanaka. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Kitagawa, Norihiko
Shinkai, Masato
Asano, Fumio
Tsuzuki, Yukihiro
Mochizuki, Kyoko
Usui, Hidehito
Yagi, Yuma
Kawami, Akio
Okumura, Kazuyoshi
Yokosuka, Tomoko
Goto, Hiroaki
Nozawa, Kumiko
Tanaka, Mio
Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title_full Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title_fullStr Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title_full_unstemmed Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title_short Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
title_sort case report: hepatectomy with rex bypass for a child with hepatoblastoma and portal vein thrombosis
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235763/
https://www.ncbi.nlm.nih.gov/pubmed/37274822
http://dx.doi.org/10.3389/fped.2023.1203212
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