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Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis
Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung rec...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235763/ https://www.ncbi.nlm.nih.gov/pubmed/37274822 http://dx.doi.org/10.3389/fped.2023.1203212 |
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author | Kitagawa, Norihiko Shinkai, Masato Asano, Fumio Tsuzuki, Yukihiro Mochizuki, Kyoko Usui, Hidehito Yagi, Yuma Kawami, Akio Okumura, Kazuyoshi Yokosuka, Tomoko Goto, Hiroaki Nozawa, Kumiko Tanaka, Mio |
author_facet | Kitagawa, Norihiko Shinkai, Masato Asano, Fumio Tsuzuki, Yukihiro Mochizuki, Kyoko Usui, Hidehito Yagi, Yuma Kawami, Akio Okumura, Kazuyoshi Yokosuka, Tomoko Goto, Hiroaki Nozawa, Kumiko Tanaka, Mio |
author_sort | Kitagawa, Norihiko |
collection | PubMed |
description | Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung recurrence rate after liver transplantation is still high. Therefore, transplantation should be avoided as much as possible. In cases of tumors in the right lobe of the liver, complete resection of the portal vein trunk may be possible by creating a Rex bypass, but with the original method, end-to-side anastomosis to the umbilical portal vein is difficult in small children. We report a case of a 2-year-old girl with hepatoblastoma in whom a Rex shunt was created by end-to-end anastomosing the recanalized umbilical vein to the portal vein stump with interposing a vein graft, and the right lobe was successfully resected along with the tumor. |
format | Online Article Text |
id | pubmed-10235763 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102357632023-06-03 Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis Kitagawa, Norihiko Shinkai, Masato Asano, Fumio Tsuzuki, Yukihiro Mochizuki, Kyoko Usui, Hidehito Yagi, Yuma Kawami, Akio Okumura, Kazuyoshi Yokosuka, Tomoko Goto, Hiroaki Nozawa, Kumiko Tanaka, Mio Front Pediatr Pediatrics Pediatric liver tumors with portal vein obstruction are often candidates for liver transplantation. However, lifelong use of immunosuppressants and invasiveness to healthy donors in the case of living-donor liver transplantation is inevitable. Moreover, when lung metastasis is involved, the lung recurrence rate after liver transplantation is still high. Therefore, transplantation should be avoided as much as possible. In cases of tumors in the right lobe of the liver, complete resection of the portal vein trunk may be possible by creating a Rex bypass, but with the original method, end-to-side anastomosis to the umbilical portal vein is difficult in small children. We report a case of a 2-year-old girl with hepatoblastoma in whom a Rex shunt was created by end-to-end anastomosing the recanalized umbilical vein to the portal vein stump with interposing a vein graft, and the right lobe was successfully resected along with the tumor. Frontiers Media S.A. 2023-05-18 /pmc/articles/PMC10235763/ /pubmed/37274822 http://dx.doi.org/10.3389/fped.2023.1203212 Text en © 2023 Kitagawa, Shinkai, Asano, Tsuzuki, Mochizuki, Usui, Yagi, Kawami, Okumura, Yokosuka, Goto, Nozawa and Tanaka. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Kitagawa, Norihiko Shinkai, Masato Asano, Fumio Tsuzuki, Yukihiro Mochizuki, Kyoko Usui, Hidehito Yagi, Yuma Kawami, Akio Okumura, Kazuyoshi Yokosuka, Tomoko Goto, Hiroaki Nozawa, Kumiko Tanaka, Mio Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title | Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title_full | Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title_fullStr | Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title_full_unstemmed | Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title_short | Case report: Hepatectomy with Rex bypass for a child with hepatoblastoma and portal vein thrombosis |
title_sort | case report: hepatectomy with rex bypass for a child with hepatoblastoma and portal vein thrombosis |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235763/ https://www.ncbi.nlm.nih.gov/pubmed/37274822 http://dx.doi.org/10.3389/fped.2023.1203212 |
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