Inhibition of microRNA-33b in humanized mice ameliorates nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) can lead to cirrhosis and hepatocellular carcinoma in their advanced stages; however, there are currently no approved therapies. Here, we show that microRNA (miR)-33b in hepatocytes is critical for the development of NASH. miR-33b is located in the intron of stero...

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Detalles Bibliográficos
Autores principales: Miyagawa, Sawa, Horie, Takahiro, Nishino, Tomohiro, Koyama, Satoshi, Watanabe, Toshimitsu, Baba, Osamu, Yamasaki, Tomohiro, Sowa, Naoya, Otani, Chiharu, Matsushita, Kazuki, Kojima, Hidenori, Kimura, Masahiro, Nakashima, Yasuhiro, Obika, Satoshi, Kasahara, Yuuya, Kotera, Jun, Oka, Kozo, Fujita, Ryo, Sasaki, Takashi, Takemiya, Akihiro, Hasegawa, Koji, Kimura, Takeshi, Ono, Koh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235800/
https://www.ncbi.nlm.nih.gov/pubmed/37263777
http://dx.doi.org/10.26508/lsa.202301902

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