Outpatient parenteral antimicrobial therapy for leishmaniasis: 13 years’ experience at a large UK infectious diseases centre

BACKGROUND: Leishmaniasis is a neglected tropical disease that is imported by travellers returning to the UK. Given the prolonged therapy required, outpatient treatment has been proven to be cost-effective and safe. METHODS: We describe cases of leishmaniasis treated through outpatient parenteral an...

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Detalles Bibliográficos
Autores principales: Parkash, Vivak, Laundy, Nicholas, Durojaiye, Oyewole Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235804/
https://www.ncbi.nlm.nih.gov/pubmed/36610796
http://dx.doi.org/10.1093/trstmh/trac128
Descripción
Sumario:BACKGROUND: Leishmaniasis is a neglected tropical disease that is imported by travellers returning to the UK. Given the prolonged therapy required, outpatient treatment has been proven to be cost-effective and safe. METHODS: We describe cases of leishmaniasis treated through outpatient parenteral antimicrobial therapy (OPAT) over a 13-y period (March 2006–September 2018) at a large teaching hospital. RESULTS: A total of 26 episodes of leishmaniasis were treated successfully, with a mean saving of 14.2 bed-days/episode. Sodium stibogluconate was the most used antileishmanial (92%). CONCLUSIONS: Treatment of chronic infections via OPAT is now commonplace and this approach may be considered for other imported infectious diseases.

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