The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis

The maintenance of redox and metabolic homeostasis is integral to embryonic development. Nuclear factor erythroid 2-related factor 2 (NRF2) is a stress-induced transcription factor that plays a central role in the regulation of redox balance and cellular metabolism. Under homeostatic conditions, NRF...

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Detalles Bibliográficos
Autores principales: Ong, Athena Jessica S., Bladen, Cerys E., Tigani, Tara A., Karamalakis, Anthony P., Evason, Kimberley J., Brown, Kristin K., Cox, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235939/
https://www.ncbi.nlm.nih.gov/pubmed/37216554
http://dx.doi.org/10.1073/pnas.2217425120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235939/
https://www.ncbi.nlm.nih.gov/pubmed/37216554
http://dx.doi.org/10.1073/pnas.2217425120

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