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The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis
The maintenance of redox and metabolic homeostasis is integral to embryonic development. Nuclear factor erythroid 2-related factor 2 (NRF2) is a stress-induced transcription factor that plays a central role in the regulation of redox balance and cellular metabolism. Under homeostatic conditions, NRF...
Autores principales: | Ong, Athena Jessica S., Bladen, Cerys E., Tigani, Tara A., Karamalakis, Anthony P., Evason, Kimberley J., Brown, Kristin K., Cox, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235939/ https://www.ncbi.nlm.nih.gov/pubmed/37216554 http://dx.doi.org/10.1073/pnas.2217425120 |
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