Cargando…

Molecular mechanism of fatty acid activation of FFAR1

FFAR1 is a G-protein-coupled receptor (GPCR) that responds to circulating free fatty acids to enhance glucose-stimulated insulin secretion and release of incretin hormones. Due to the glucose-lowering effect of FFAR1 activation, potent agonists for this receptor have been developed for the treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumari, Punita, Inoue, Asuka, Chapman, Karen, Lian, Peng, Rosenbaum, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235965/
https://www.ncbi.nlm.nih.gov/pubmed/37216523
http://dx.doi.org/10.1073/pnas.2219569120