Paf1 complex subunit Rtf1 stimulates H2B ubiquitylation by interacting with the highly conserved N-terminal helix of Rad6

Histone modifications coupled to transcription elongation play important roles in regulating the accuracy and efficiency of gene expression. The monoubiquitylation of a conserved lysine in H2B (K123 in Saccharomyces cerevisiae; K120 in humans) occurs cotranscriptionally and is required for initiatin...

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Detalles Bibliográficos
Autores principales: Fetian, Tasniem, McShane, Brendan M., Horan, Nicole L., Shodja, Donya N., True, Jason D., Mosley, Amber L., Arndt, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235976/
https://www.ncbi.nlm.nih.gov/pubmed/37216505
http://dx.doi.org/10.1073/pnas.2220041120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235976/
https://www.ncbi.nlm.nih.gov/pubmed/37216505
http://dx.doi.org/10.1073/pnas.2220041120

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