Probing differences among Aβ oligomers with two triangular trimers derived from Aβ

The assembly of the β-amyloid peptide (Aβ) to form oligomers and fibrils is closely associated with the pathogenesis and progression of Alzheimer’s disease. Aβ is a shape-shifting peptide capable of adopting many conformations and folds within the multitude of oligomers and fibrils the peptide forms...

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Detalles Bibliográficos
Autores principales: Kreutzer, Adam G., Guaglianone, Gretchen, Yoo, Stan, Parrocha, Chelsea Marie T., Ruttenberg, Sarah M., Malonis, Ryan J., Tong, Karen, Lin, Yu-Fu, Nguyen, Jennifer T., Howitz, William J., Diab, Michelle N., Hamza, Imane L., Lai, Jonathan R., Wysocki, Vicki H., Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235986/
https://www.ncbi.nlm.nih.gov/pubmed/37216514
http://dx.doi.org/10.1073/pnas.2219216120

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