Microtubule detyrosination drives symmetry breaking to polarize cells for directed cell migration

To initiate directed movement, cells must become polarized, establishing a protrusive leading edge and a contractile trailing edge. This symmetry-breaking process involves reorganization of cytoskeleton and asymmetric distribution of regulatory molecules. However, what triggers and maintains this as...

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Detalles Bibliográficos
Autores principales: Lavrsen, Kirstine, Rajendraprasad, Girish, Leda, Marcin, Eibes, Susana, Vitiello, Elisa, Katopodis, Vasileios, Goryachev, Andrew B., Barisic, Marin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235987/
https://www.ncbi.nlm.nih.gov/pubmed/37216553
http://dx.doi.org/10.1073/pnas.2300322120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235987/
https://www.ncbi.nlm.nih.gov/pubmed/37216553
http://dx.doi.org/10.1073/pnas.2300322120

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