TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization

Toll-like receptor 3 (TLR3) is an innate immune receptor that recognizes double-stranded RNA (dsRNA) and induces inflammation in immune and normal cells to initiate anti-microbial responses. TLR3 acts also as a death receptor only in cancer cells but not in their normal counterparts, making it an at...

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Detalles Bibliográficos
Autores principales: Thierry, Sylvain, Maadadi, Sarah, Berton, Aurore, Dimier, Laura, Perret, Clémence, Vey, Nelly, Ourfali, Saïd, Saccas, Mathilde, Caron, Solène, Boucard-Jourdin, Mathilde, Colombel, Marc, Werle, Bettina, Bonnin, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236204/
https://www.ncbi.nlm.nih.gov/pubmed/37275475
http://dx.doi.org/10.15698/mic2023.06.797

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