Lanosterol synthase loss of function decreases the malignant phenotypes of HepG2 cells by deactivating the Src/MAPK signaling pathway

Cholesterol is critical for tumor cells to maintain their membrane components, cell morphology and activity functions. The inhibition of the cholesterol pathway may be an efficient strategy with which to limit tumor growth and the metastatic process. In the present study, lanosterol synthase (LSS) w...

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Detalles Bibliográficos
Autores principales: Sun, Xiaomei, Zhang, Jun, Liu, Hui, Li, Mingcong, Liu, Li, Yang, Zhen, Hu, Weikang, Bai, Hongmei, Xu, Jiansheng, Xing, Jun, Xu, Zhijun, Mo, Aizhu, Guo, Ziyi, Bai, Yajie, Zhou, Qing, Wang, Yuan, Zhang, Shengquan, Zhang, Sumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236266/
https://www.ncbi.nlm.nih.gov/pubmed/37274468
http://dx.doi.org/10.3892/ol.2023.13881

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