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Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion

High-temperature laser bed powder fusion (HT-LPBF) technology is an ideal method for processing poly-ether-ether-ketone (PEEK) implants with personalized bionic structures, but the biological inertia of PEEK limits its medical applications. In this study, we evaluated the mechanical and biological p...

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Autores principales: Chen, Zhiyuan, Wang, Haoze, Su, Jin, Shu, Zixing, Hou, Jiayi, Chen, Peng, Li, Zhaoqing, Yan, Chunze, Shi, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236334/
https://www.ncbi.nlm.nih.gov/pubmed/37273982
http://dx.doi.org/10.18063/ijb.699
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author Chen, Zhiyuan
Wang, Haoze
Su, Jin
Shu, Zixing
Hou, Jiayi
Chen, Peng
Li, Zhaoqing
Yan, Chunze
Shi, Yusheng
author_facet Chen, Zhiyuan
Wang, Haoze
Su, Jin
Shu, Zixing
Hou, Jiayi
Chen, Peng
Li, Zhaoqing
Yan, Chunze
Shi, Yusheng
author_sort Chen, Zhiyuan
collection PubMed
description High-temperature laser bed powder fusion (HT-LPBF) technology is an ideal method for processing poly-ether-ether-ketone (PEEK) implants with personalized bionic structures, but the biological inertia of PEEK limits its medical applications. In this study, we evaluated the mechanical and biological properties of a novel akermanite (AKM)/PEEK composite for HT-LPBF. The results showed that tiny AKM particles are evenly attached to the surface of the PEEK particle. The delayed peak crystallization temperature and stable sintering window ensure the processing feasibility of the AKM/PEEK composites. The tensile strength and Young’s modulus are in the range of 30.83–98.73 MPa and 2.27–3.71 GPa, respectively, which can match the properties of cancellous bones and meet their implanting requirement. The CCK-8 experiments demonstrated the biocompatibility of the composites and the good proliferation of bone marrow stromal cells. The dense hydroxyapatite network layer and petal-like hydroxyapatite demonstrates biological activity, indicating that the composite has a good potential in the orthopedics fields.
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spelling pubmed-102363342023-06-03 Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion Chen, Zhiyuan Wang, Haoze Su, Jin Shu, Zixing Hou, Jiayi Chen, Peng Li, Zhaoqing Yan, Chunze Shi, Yusheng Int J Bioprint Research Article High-temperature laser bed powder fusion (HT-LPBF) technology is an ideal method for processing poly-ether-ether-ketone (PEEK) implants with personalized bionic structures, but the biological inertia of PEEK limits its medical applications. In this study, we evaluated the mechanical and biological properties of a novel akermanite (AKM)/PEEK composite for HT-LPBF. The results showed that tiny AKM particles are evenly attached to the surface of the PEEK particle. The delayed peak crystallization temperature and stable sintering window ensure the processing feasibility of the AKM/PEEK composites. The tensile strength and Young’s modulus are in the range of 30.83–98.73 MPa and 2.27–3.71 GPa, respectively, which can match the properties of cancellous bones and meet their implanting requirement. The CCK-8 experiments demonstrated the biocompatibility of the composites and the good proliferation of bone marrow stromal cells. The dense hydroxyapatite network layer and petal-like hydroxyapatite demonstrates biological activity, indicating that the composite has a good potential in the orthopedics fields. Whioce Publishing Pte. Ltd. 2023-03-03 /pmc/articles/PMC10236334/ /pubmed/37273982 http://dx.doi.org/10.18063/ijb.699 Text en Copyright:© 2023, Chen Z, Wang H, Su J, et al., https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, permitting distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Zhiyuan
Wang, Haoze
Su, Jin
Shu, Zixing
Hou, Jiayi
Chen, Peng
Li, Zhaoqing
Yan, Chunze
Shi, Yusheng
Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title_full Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title_fullStr Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title_full_unstemmed Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title_short Evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
title_sort evaluation of mechanical and biological properties of akermanite/poly-ether-ether- ketone composite fabricated by high- temperature laser powder bed fusion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236334/
https://www.ncbi.nlm.nih.gov/pubmed/37273982
http://dx.doi.org/10.18063/ijb.699
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