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Flow performance of porous implants with different geometry: Line, surface, and volume structures

Additive manufacturing has enormous advantage of personalized adaptation. Particularly, porous implants have been widely used in clinical practice. Porous implant has the advantages and abilities to promote tissue growth and mass transfer, which are closely related to pore morphology. The purpose of...

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Detalles Bibliográficos
Autores principales: Tang, Zhuxun, Zhou, Yueting, Ma, Lifang, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236350/
https://www.ncbi.nlm.nih.gov/pubmed/37273989
http://dx.doi.org/10.18063/ijb.700
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author Tang, Zhuxun
Zhou, Yueting
Ma, Lifang
Li, Jian
author_facet Tang, Zhuxun
Zhou, Yueting
Ma, Lifang
Li, Jian
author_sort Tang, Zhuxun
collection PubMed
description Additive manufacturing has enormous advantage of personalized adaptation. Particularly, porous implants have been widely used in clinical practice. Porous implant has the advantages and abilities to promote tissue growth and mass transfer, which are closely related to pore morphology. The purpose of this study is to investigate the effects of three porous structures, i.e., line structure, surface structure, and volume structure, on the flow properties of implants at different porosity. Therefore, a unit cell was selected from each type of structure (oct truss [OT], gyroid [G], and schwarz p [P]) as a typical cell, where OT is a line structure, G is a surface structure, and P is a volume structure. The scaffolds with different porosity of these cells were customized, and the shape parameters were measured and calculated. Then, the flow performance of three different scaffolds in Dulbecco’s modified Eagle’s medium was simulated by using computational fluid dynamics, and the flow velocity, permeability, and wall shear stress, which can reflect their biological properties, were calculated and compared. The results showed that the pore shape and porosity of porous implants greatly affected the physical parameters and performance of structures. These findings will contribute to unit cell selection and future performance optimization of porous implants.
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spelling pubmed-102363502023-06-03 Flow performance of porous implants with different geometry: Line, surface, and volume structures Tang, Zhuxun Zhou, Yueting Ma, Lifang Li, Jian Int J Bioprint Research Article Additive manufacturing has enormous advantage of personalized adaptation. Particularly, porous implants have been widely used in clinical practice. Porous implant has the advantages and abilities to promote tissue growth and mass transfer, which are closely related to pore morphology. The purpose of this study is to investigate the effects of three porous structures, i.e., line structure, surface structure, and volume structure, on the flow properties of implants at different porosity. Therefore, a unit cell was selected from each type of structure (oct truss [OT], gyroid [G], and schwarz p [P]) as a typical cell, where OT is a line structure, G is a surface structure, and P is a volume structure. The scaffolds with different porosity of these cells were customized, and the shape parameters were measured and calculated. Then, the flow performance of three different scaffolds in Dulbecco’s modified Eagle’s medium was simulated by using computational fluid dynamics, and the flow velocity, permeability, and wall shear stress, which can reflect their biological properties, were calculated and compared. The results showed that the pore shape and porosity of porous implants greatly affected the physical parameters and performance of structures. These findings will contribute to unit cell selection and future performance optimization of porous implants. Whioce Publishing Pte. Ltd. 2023-03-06 /pmc/articles/PMC10236350/ /pubmed/37273989 http://dx.doi.org/10.18063/ijb.700 Text en Copyright:© 2023, Tang Z, Zhou Y, Ma L, et al., https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, permitting distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tang, Zhuxun
Zhou, Yueting
Ma, Lifang
Li, Jian
Flow performance of porous implants with different geometry: Line, surface, and volume structures
title Flow performance of porous implants with different geometry: Line, surface, and volume structures
title_full Flow performance of porous implants with different geometry: Line, surface, and volume structures
title_fullStr Flow performance of porous implants with different geometry: Line, surface, and volume structures
title_full_unstemmed Flow performance of porous implants with different geometry: Line, surface, and volume structures
title_short Flow performance of porous implants with different geometry: Line, surface, and volume structures
title_sort flow performance of porous implants with different geometry: line, surface, and volume structures
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236350/
https://www.ncbi.nlm.nih.gov/pubmed/37273989
http://dx.doi.org/10.18063/ijb.700
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